The circadian clock
ticks in virtually every body cell
The biological clock, also known as the circadian clock, regulates the timing of many cellular and molecular mechanisms and plays a vital role in maintaining human health. Disruption of your circadian rhythms is associated with diseases like sleep disorders, depression, diabetes, neurodegenerative diseases, obesity and cancer. A dysregulated circadian clock can impair both physical and cognitive performance.
We all have our own
circadian rhythm
Circadian rhythms and the timing of our molecular processes differ from person to person. Knowing your personal circadian rhythms and adjusting activities such as sleep, exercise, daylight or medicine intake according to your internal timing can improve health and reduce recovery or therapy time in patients.
TimeTeller profiles your unique circadian rhythm
We have developed a non-invasive method to profile the personal circadian rhythm. Using an easy, risk-free at-home test, you send your samples to TimeTeller for analysis and get a personal report back.
TimeTeller profiles your circadian clock using molecular analysis of saliva samples and mathematical modelling to provide personalized recommendations for lifestyle adjustments or medical treatment timing.
TimeTeller in cancer care
Adjusting the timing of medical treatment to the circadian rhythm of the individual patient can optimize efficacy and diminish unwanted side effects, leading to improved life quality for patients and reduced healthcare costs.
We currently participate in clinical studies to validate and bring the benefits of our method to cancer patients in Germany and beyond.
Time Teller is an innovation project in the Digital Health Accelerator Program of the BIH
We are looking for:
Cooperations with pharmaceutical industry and Medtech for further development of a companion diagnostic solution, as well as further testing of the TimeTeller kit.
National and international clinical partners to further develop and test TimeTeller in clinical trials in oncology, also in additional cancer types.
Clinical study partners in Parkinson Disease and other circadian-related pathologies.
Pharma partners for our Research product: early clinical trial drug assessment /CROs.
Additional Team members with Business and Regulatory expertise.
Contact
Prof. Dr. Angela Relógio
Professor for Systems Medicine
Group Leader – Systems Biology of Cancer
MSH-Medical School Hamburg
Institute for Theoretical Biology-ITB
Molecular Cancer Research Centre-MKFZ
Charité Medical University of Berlin
email: angela.relogio@charite.de