Press release for our study on the impact of sleep apnea on our body´s biological clocks, published in the scientific journal EBioMedicine, The Lancet, which highlights the urgent need to find new strategies that improve and anticipate the diagnosis of this obstructive respiratory disease, one of the most disturbed sleep disorders prevalent in the world, but still underdiagnosed.
Our collaborative work with the groups of Claudia Cavadas and Ana-Rita Alvaro was published in EBioMedicine. “Long-term continuous positive airway pressure treatment ameliorates biological clock disruptions in obstructive sleep apnea.” Gaspar LS, Hesse J, Yalçin M, Santos B, Carvalhas-Almeida C, Ferreira M, Moita J, Relógio A, Cavadas C, Álvaro AR.
Our work on “Diurnal variations in the expression of core-clock genes correlate with resting muscle properties and predict fluctuations in exercise performance across the day.” by Alireza Basti, et al. was published in BMJ Open Sport Exerc Med
Our joint work on “New Strategies to Develop Circadian Biomarkers for Obstructive Sleep Apnea”, with the groups of Claudia Cavadas and Ana Rita Álvaro, received the award Thomé Villar / Boehringer Ingelheim 2020, 1st Prize, Portuguese Society of Pulmonology, for the best scientific research work on the Pulmonology field
Our review on “An Optimal Time for Treatment-Predicting Circadian Time by Machine Learning and Mathematical Modelling” by Janina Hesse et al is published in Cancers
Our collaborative work with the group of Telma Quintela is online. The Rhythmicity of Clock Genes is Disrupted in the Choroid Plexus of the APP/PS1 Mouse Model of Alzheimer’s Disease. Furtado A, Astaburuaga R, Costa A, Duarte AC, Gonçalves I, Cipolla-Neto J, Lemos MC, Carro E, Relógio A, Santos CRA, Quintela T. J Alzheimers Dis.
Müge’s paper is online. Analysis of the Circadian Regulation of Cancer Hallmarks by a Cross-Platform Study of Colorectal Cancer Time-Series Data Reveals an Association with Genes Involved in Huntington’s Disease. Yalçin M, El-Athman R, Ouk K, Priller J, Relógio A. Cancers
Alireza’s paper is online. The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in A Zebrafish Xenograft Colon Cancer Model. Basti A, Fior R, Yalҫin M, Póvoa V, Astaburuaga R, Li Y, Naderi J, Godinho Ferreira M, Relógio A. Cancers
Our collaborative review work is online. The Circadian Clock, the Immune System, and Viral Infections: The Intricate Relationship Between Biological Time and Host-Virus Interaction. Mazzoccoli G, Vinciguerra M, Carbone A, Relógio A. Pathogens.